Pharmacology & Pharmacy (PP)

Publisher: Scientific Research Publishing

Journal description

RG Journal Impact: 0.46 *

How does the ingredient work? Sildenafil is used to treat impotence (erectile dysfunction). The causes of impotence are many. In men over 50 years, it is usually other diseases, such as atherosclerosis or hypertension. Then impotence is an important early warning sign for these diseases. They should definitely be treated. In about 20 percent of cases, impotence is psychologically conditioned, especially in the age group up to 35 years. The erection of the penis is based on a rapid influx of blood into the erectile tissue. For this purpose, the arteries must expand. This is only possible if the surrounding muscles relax. In sexual stimulation, therefore, the messenger nitric oxide (NO) is released. He is activating a second messenger, the cGMP. Only the cGMP causes the muscle cells in the erectile tissue to relax, thus enabling blood flow and erection. To end the erection, cGMP is degraded again via the enzyme phosphodiesterase 5 (PDE-5). Tadalafil is a PDE-5 inhibitor. It blocks the enzyme phosphodiesterase 5. This keeps more cGMP circulating, increasing muscle relaxation and improving erection. Due to this mechanism, Tadalafil only works in sexually excited men. It has no lust-increasing effect and therefore can not force an erection. Men take one tablet about 1 hour before the desired sexual intercourse. The effect lasts up to 5 hours. application areas • impotence Warning! This medicinal product, even when used as intended, may affect the visual performance and thus the ability to react in traffic or in the operation of machinery. Even if used as intended, this medicinal product may alter the ability to react so far as to impair the ability to drive or operate machinery. This applies even more in combination with alcohol. When is the medication not suitable for you (contraindication)? • Hereditary diseases of the retina (retina) of the eye, which destroy the function and the structures of the cells. • Simultaneous treatment with other potentiating drugs • Children and adolescents under 18 years • low blood pressure (hypotension) • Patients who are prone to permanent erections (priapism) or whose penis is anatomically deformed should use this medicine with caution. A permanent erection must be treated immediately by a doctor, otherwise tissue damage and loss of power may result. • Severe cardiovascular diseases • severe liver dysfunction • Beware of gastrointestinal ulcers pregnancy and breast feeding period • Not indicated for women side effects Listed are the most important known side effects. They can occur, but they do not have to, because each person responds differently to medication. Sometimes people are allergic to medication. If you feel any signs of allergic reaction, tell your doctor or pharmacist immediately. • A headache • skin redness with flushing sensation (flush) • vision problems (occasionally) • overstimulation of the stomach. It is characterized by fullness, stomach pressure and premature satiety, heartburn, upper abdominal pain, nausea and rarely vomiting. (Occasionally) • Nasal congestion (Uncommon) • Painful, long-lasting erection requiring treatment (priapism) (rare) interactions The effect of drugs against cardiovascular disease, which include nitrates or NO donors, may increase sharply. Concomitant use can cause severe hypotension with collapse. Therefore, patients with these cardiovascular drugs should not use sildenafil.

RG Journal impact history

2019Available summer 2020
20150.46
20140.38
20130.36
20120.34

RG Journal impact over time

RG Journal impact
RG Journal impact over timeGraph showing a linear path with a yearly representation of impact points of the journal

Additional details

Cited half-lifedata not available
Immediacy indexdata not available
Eigenfactordata not available
Article influencedata not available
Websitehttp://www.scirp.org/journal/pp
Website description
ISSN2157-9423

Publications in this journal

Are generic medicines the same as branded medicines? Our products and branded products are identical and your body will notice no difference. Sildenafil Citrate (Generic Viagra) and Viagra ™ ® both contain 100 mg Sildenafil Citrate. Generic Viagra ™ is a generic generic version of Viagra ™ ® - just as ibuprofen is the generic name for Advil®. The same applies to every single medicine from our range. All medications are simple formulas made from common chemical ingredients. Making an exact copy of a medicine is very easy. Our state of the art laboratories are able to easily replicate all major branded medicines, and complex and regular research assures us that our products are an exact duplicate of the original. Why pay the full price for a branded product in retail if you can now get a generic version with 60% off? The pills you order from us will look a little different than their brand equivalents. Generics do not look like the branded products, even though they have the same active ingredients and mode of action. In addition, the same branded medicines may look different if produced in different countries. For example, Celexa 20MG is a peach-colored pill in the US, while the Canadian pill is white and a bit smaller. Both pills are Celexa 20MG, both have the same active ingredients and both were produced by the same company. But, whatever the reason, the manufacturer has decided to produce the Canadian pill in a different color. Even if you compare 2 different generics, they will look different if they were made by different companies.
What are generic medications? When a pharmaceutical company first develops a remedy, that company is the only one in the country entitled to produce that remedy over a certain number of years. After this period, other companies may make the same drug. These funds are called generics. The original (for example, Viagra) is called a brand name drug. Branded medicines and their generic medicines are IDENTICAL in their ingredients. The generic pills may look different (because they were made by another company) but they contain exactly the same ingredients that work the same way. The only difference between brand name products and generic drugs is that generic drugs are always cheaper.
Klaus from Wuppertal: Actually, it's almost always .... "Actually, I have no problems in the sense that nothing works anymore, but what is and was my problem is that I can not sustain the sex, so I get excited, get an erection and go, but after a short while he stops To be hard and then I had to stop mostly and start again.My wife accepted this at first and we tried to live with it, but it was not really great.I asked my doctor and he checked me out a bit and me Well, frankly, I'm feeling really good in bed for the first time and sticking to it, these monster-stand tales etc. are total nonsense, it's just like always, just that I stick around and feel like a whole man. " Martin from Berlin: Again from the beginning "I do not have any problems, I guess everybody says that, but it's the same for me, I've been married for 24 years and there have never been any problems, ok, days when it did not work that way, but that's normal after the breakup From my wife I was back in the market and it was very unusual to advertise again etc. On the first date where it came I totally "failed" Not that I was not excited, but it was so unusual and I had Well, the whole thing went in my pants and I took a sildenafil for the second date, which was really great, still unfamiliar, but still had the pressure to perform but stood like a one. " David: Not bad at all Hello, I discovered the page and am really surprised. Great service, delivery directly from Germany and top products, the praise I have to pronounce you, keep it up. I have problems for 3 years and my doctor prescribed Viagra for me, which is really expensive on the market. My orders at online sites were ok too, but I already had 2x to customs and got problems. I am glad that I do not need this anymore and I am on the safe side.
Question: How is an online consultation held? Answer: Online counseling is a new concept that allows patients to receive medication via the Internet. In doing so, the patient is not subjected to a physical examination by his doctor in the traditional sense, but answers online a questionnaire written by specialists in the medical field. Although online counseling can never replace traditional, personal consultation, it still provides a means to help patients receive certain treatments that can be prescribed without physical examinations. Question: Is the sale of prescription drugs on the Internet allowed by law? Answer: Yes, apart from narcotics and other strictly regulated medications, medications that are offered online are legally permitted provided they are prescribed by a licensed physician. All medicines are obtained from a wholesale pharmacist or directly from the manufacturer. Therefore, you can be sure that you will receive high quality medication lawfully. Question: What about shipping costs and business policies? Answer: Our shipping costs and online prescriptions (online prescriptions) are INCLUDED in the price. If your order is confirmed, your order will be sent within 48 hours. The delivery date depends on your place of residence and the location of the supplier, as well as the date of receipt of your payment. How we strive to deliver directly to your doorstep within 10-18 business days. The delivery is accompanied by information regarding the application, the dosage and the risks. Although our shipping is operated worldwide, some countries are not listed in our directory for various reasons. If your country is not listed, please contact us. Question: Which payment methods are accepted? Answer: At the moment we only accept bank transfers. As soon as the transfer has arrived, the goods will be sent the same day. For online transfers this can happen the same day the order. Question: How long are cancellations and cancellations possible? Answer: As long as your order has not been processed, you can unsubscribe. Please contact [email protected] Your order can be terminated at any time until receipt of the money / shipping. Once an order has been processed, it can no longer be canceled. Question: Can I return my medication for a refund? Answer: No. Under United States federal law, we may not reimburse or exchange prescription medicines. However, if your delivery is defective or has not arrived at all, we will, at your option, either re-ship at our expense or reimburse you. Question: What about your security and privacy? Answer: Protecting your personal information and security are extremely important to us. We do not tolerate any compromise. Our site uses industry-standard security measures, including SSL (Secure Sockets Layer), and uses an encrypted order form to collect information. The product transaction is also encrypted. For business reasons, we store with us the e-mail address of the customer, the credit card details and the delivery address. The information provided by the customer will be entered into our verified secure network, with all transaction data stored in our secure database. Information provided by customers will never be disclosed to third parties, sold or forwarded outside of our intranet. All account information is kept safe from unauthorized persons and used only by us. Question: Who will I order today, when will I receive my delivery? Answer: We will process your order within 48 hours after your payment has been received. The shipping, depending on your place of residence, can take between 5-20 days. Your order will be discreetly packaged for your protection and privacy, and sent by registered mail from one of our international delivery centers. Not only do our customers love our products, they also appreciate the efforts we make to get the products to customers as quickly and discreetly as possible. Happy customers make good business, and we do everything we can to fully satisfy our customers. Although it is very unlikely, we kindly ask you to contact us if you still have not received your delivery after 20 business days. We will do everything we can to support you and clarify the situation.
In Germany alone, around four to six million men between the ages of 30 and 70 are affected by an ED. With increasing age, the probability of a power disorder increases significantly. A medical study showed that by the age of 40, only one in three men interviewed suffered from an ED, whereas among the 40 to 70 year olds, 50 percent were men. Since these are official numbers, the dark tick is at a probable multiplier of 2-3. According to this, 12 to 18 million men in Germany alone would be affected at times, often or always. These amazing numbers clearly show that erectile dysfunction is not an "individual phenomenon" but a very common situation. But even if this shows how many men are affected, we live in a time that allows men to deal positively with this life situation through the use of opportunities for stimulation and drugs.
How does the ingredient work? Tadalafil is used to treat impotence (erectile dysfunction). The causes of impotence are many. In men over 50 years, it is usually other diseases, such as atherosclerosis or hypertension. Then impotence is an important early warning sign for these diseases. They should definitely be treated. In about 20 percent of cases, impotence is psychologically conditioned, especially in the age group up to 35 years. The erection of the penis is based on a rapid influx of blood into the erectile tissue. For this purpose, the arteries must expand. This is only possible if the surrounding muscles relax. In sexual stimulation, therefore, the messenger nitric oxide (NO) is released. He is activating a second messenger, the cGMP. Only the cGMP causes the muscle cells in the erectile tissue to relax, thus enabling blood flow and erection. To end the erection, cGMP is degraded again via the enzyme phosphodiesterase 5 (PDE-5). Tadalafil is a PDE-5 inhibitor. It blocks the enzyme phosphodiesterase 5. This keeps more cGMP circulating, increasing muscle relaxation and improving erection. Due to this mechanism, Tadalafil only works in sexually excited men. It has no lust-increasing effect and therefore can not force an erection. Tadalafil is also referred to as a "weekend pill" due to its long duration of action of up to 24 hours. This makes it suitable for men who want to have intercourse several times within two days. It is recommended to take one tablet 30 minutes to 12 hours before. application areas • impotence When is the medication not suitable for you (contraindications)? • Simultaneous treatment with other potentiating drugs • Children and adolescents under 18 years • low blood pressure (hypotension) • Patients who are prone to permanent erections (priapism) or whose penis is anatomically deformed should use this medicine with caution. A permanent erection must be treated immediately by a doctor, otherwise tissue damage and loss of power may result. • Beware of severe liver, kidney and heart disease pregnancy and breast feeding period • Not indicated for women side effects Listed are the most important known side effects. They can occur, but they do not have to, because each person responds differently to medication. Sometimes people are allergic to medication. If you feel any signs of allergic reaction, tell your doctor or pharmacist immediately. • A headache • Dizziness • Muscle aches • overstimulation of the stomach. It is characterized by fullness, stomach pressure and premature satiety, heartburn, upper abdominal pain, nausea and rarely vomiting. • obstruction of the nose • skin redness with flushing sensation (flush) • back pain • Eye inflammation (Uncommon) interactions The effect of drugs against cardiovascular disease, which include nitrates or NO donors, may increase sharply. Concomitant use can cause severe hypotension with collapse. Therefore, patients with these cardiovascular drugs should not use tadalafil. Certain medicines for infections with bacteria, viruses or fungi, as well as taking grapefruit juice may increase the side effects of tadalafil.
The headline that makes "Viagra" men happy even without women involves two topics at the same time. Namely on the one hand the never-ending male-female topic and on the other hand the results of an American study. This had published results on side effects of one of the world's best-known drugs on the market - Viagra. The researchers from the University of Wisconsin-Madison had shown in animal experiments that Viagra increases the oxytocin level of the rats studied. The hormone oxytocin is also called "faith hormone" or "binding hormone". When sharing caresses - not just during sex - it is released by the body itself. For example, it plays a major role in the relationship building between parents and children or between couples. Critics of the study point out that the increase in the oxytocin level of the experimental animals is not due to a side effect of Viagra, but to the increased "cuddle factor", which in turn could be described as a side effect of the increased sexual activity of the animals. This theory provides the attentive reader clear evidence that once again a very one-dimensional research on the media-effective drug Viagra was performed. Viagra is ultimately a treatment option for organically induced erectile dysfunction and ignores all psychological triggers and couple problems - which, moreover, more often lead to erectile dysfunction. Therefore, connections between the use of Viagra, the oxytocin level of the treated and his sense of happiness in his relationship with women are to be regarded as provocative headlines.
Whether Viagra makes fit in the head, was so far controversial. But now it is proven. Viagra is a memory-assisting remedy. But it is still unclear how this effect comes about. What is clear is that Viagra slows down the process of breaking down cGMP and thus acts as a memory aid. This benefits old and forgetful patients in particular. But not only men swallow the Viagra pill at this time. Also, women take Viagra, because of the fact that Viagra promotes blood circulation. As a result, you could even get orgasms, which have so far failed due to poor circulation. Also, the remedy may help seemingly infertile women. If they suffer from a too thin uterine lining, the remedy promises true miracles. It helps the body to thicken the mucous membrane and thus make it possible for women to get pregnant. This has not happened before. A case from the States reports of a woman whose doctor had labeled her as infertile. Even after two artificial inseminations nothing happened. But then by just taking Viagra, the woman could become pregnant. Why? She suffered from a too thin uterine lining.
The anti-doping agency WADA has found out that athletes Viagra take to boost their performance in the sport. Therefore, this agency is considering putting the drug for Erectile Dysfunction on a list of illegal substances. From a scientific point of view, however, it is still unclear whether the drug increases the athletic performance. Therefore, no results are to be expected until next year and Viagra is allowed further even for the active athletes. Because this ED pill promotes blood circulation, men may assume that it also improves endurance. When cyclists have taken the Viagra, had a 15% performance increase on a track over 6km. However, the other competitive athlete saw no improvement.
Scientists of nanotechnology have found a new drug that could lead to almost immediate treatment of erectile dysfunction. This remedy would be tested on animals and promises a lot for the first time. The patient would only apply a few parts in the form of cream on the limb and the effect (a hard limb) would be seen immediately. No more waiting 30 or more minutes. But unfortunately, this research will most likely take years until we get a competitor to Viagra and other power resources.
Natural products and slimming capsules You prefer the healing powers of nature? Here you are in the right place, because we offer you best potency remedies on a natural basis or slimming capsules. However, we decided to remove the LiDa slimming product from the program because we can no longer check the content of sibutramine. You can find more information quickly and easily in the directory, you can simply use the search function in the menu above. What are generic drugs? If you are unfamiliar with the term generic, you will find detailed information in the menu under: "Information" Basically, it is that medicines are referred to as generic drugs, if they have a comparable active ingredient concentration as the original product. In addition to the over-the-counter Viagra and Cialis orders, we also provide you with ample information about erectile dysfunction (impotence), medications and suitable therapies as well as important information about sexual enhancers under the menu item: "Information". We rely on your trust and therefore ask you to observe the following instructions: You should consult a doctor of your choice before purchasing a sexual enhancement order - no matter which online pharmacy or shop. Consult with him to see if the medications you want to buy here are right for your organism. If your doctor has given you his suggestions and instructions, please enter your Potency Order online here. Many doctors will advise you anyway to buy the sexual enhancer online, or to search for a Viagra shipping, because these are hardly affordable in the conventional pharmacies today. In addition, this way you can be sure that you will receive the optimal sexual enhancer for your needs. The team is constantly striving to expand the offer of high quality and cheap generic drugs for you. With it we can guarantee you a self-confident lifestyle, a fulfilling partnership and a sex life that suits your desires. Put your trust in transparency, transparency and information! You will not be disappointed. Of course we hope that you like the new slim design of Potenzmittel pharmacy as much as we do, and we thank you for your trust. We at Potency Online, your internet pharmacy, wish you lasting health and many happy moments.

Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed.